Mapping three-dimensional temperature in microfluidic chip.

Jinbo Wu, Tsz Yan Kwok, Xiaolin Li, Wenbin Cao, Yu Wang, Junying Huang, Yaying Hong, Dongen Zhang, Weijia Wen

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


Three-dimensional (3D) temperature mapping method with high spatial resolution and acquisition rate is of vital importance in evaluating thermal processes in micro-environment. We have synthesized a new temperature-sensitive functional material (Rhodamine B functionalized Polydimethylsiloxane). By performing optical sectioning of this material, we established an advanced method for visualizing the micro-scale 3D thermal distribution inside microfluidic chip with down to 10 ms temporal resolution and 2 ~ 6 °C temperature resolution depending the capture parameters. This method is successfully applied to monitor the local temperature variation throughout micro-droplet heat transfer process and further reveal exothermic nanoliter droplet reactions to be unique and milder than bench-top experiment.
Original languageEnglish (US)
JournalScientific Reports
Issue number1
StatePublished - Nov 25 2013
Externally publishedYes


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