We employ renormalized viscosity to perform large eddy simulations (LESs) of decaying homogeneous and isotropic turbulence in a cubical domain. We perform a direct numerical simulation (DNS) on 5123 and 2563 grids and LES on 323, 643, and 1283 grids with the same initial conditions in the resolved scales for a flow with Taylor Reynolds number Reλ = 210. We observe good agreement between LES and DNS results for the temporal evolution of turbulence kinetic energy Eu(t), kinetic energy spectrum Eu(k), and kinetic energy flux Πu(k). Also, the large-scale structures of the flow in LES are similar to those in DNS. These results establish the suitability of our renormalized viscosity scheme for LES.