Label-free electronic detection of DNA using simple double-walled carbon nanotube resistors

Xiaochen Dong*, Dongliang Fu, Yanping Xu, Jinquan Wei, Yumeng Shi, Peng Chen, Lain-Jong Li

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

35 Scopus citations

Abstract

Label-free electrical detection of DNA hybridization using resistive sensing devices based on drop-casted doubled-walled carbon nanotube (DWNT) networks and as-grown films is presented. Sensitive, selective, and reliable detection of DNA hybridization is achieved by simple two-terminal measurements, which is suitable for the hand-held type of device applications. Our approach is able to detect DNA concentrations ranging from 50 to 500 nM. Utilizing location-selective capping by photoresists, we designed experiments to reveal the sensing mechanism and found that the carbon nanotube (CNT)-metal junction may not play a dominant role in sensing as it does in single-walled carbon nanotube-based transistor devices. A charge-transfer model is proposed to explain the detection mechanism.

Original languageEnglish (US)
Pages (from-to)9891-9895
Number of pages5
JournalJournal of Physical Chemistry C
Volume112
Issue number26
DOIs
StatePublished - Jul 3 2008

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Energy(all)
  • Physical and Theoretical Chemistry
  • Surfaces, Coatings and Films

Fingerprint Dive into the research topics of 'Label-free electronic detection of DNA using simple double-walled carbon nanotube resistors'. Together they form a unique fingerprint.

Cite this