We consider the joint application of power control, adaptive modulation and diversity combining in the uplink of a two-cell wireless network. The goal is to derive a practical low-complexity, bandwidth-efficient, and battery-power efficient transmission scheme addressing the particular challenges of uplink transmission. Employing dynamic spectral reuse, we allow for coordination of the transmit power levels to minimize the sum transmit power, and thus implicitly the interference to co-existing systems and cells. Based on assumed transmitter knowledge of the channel fading, the proposed schemes adaptively select the signal constellation. We show that the novel scheme provides significant average transmit power reductions, yielding a substantial increase of battery lifetime, and decreased interference, while maintaining high average spectral efficiency, and compliance with bit error rate constraints.