Abstract
The monocarboxylate transporter 1 (MCT1) is highly expressed in the outer retina, suggesting that it plays a critical role in photoreceptors. We examined MCT1+/− heterozygotes, which express half of the normal complement of MCT1. The MCT1+/− retina developed normally and retained normal function, indicating that MCT1 is expressed at sufficient levels to support outer retinal metabolism.
Original language | English (US) |
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Title of host publication | Advances in Experimental Medicine and Biology |
Publisher | Springer International Publishing |
Pages | 375-380 |
Number of pages | 6 |
ISBN (Print) | 9783319754017 |
DOIs | |
State | Published - May 2 2018 |