Promoter sequences are the main regulatory elements of gene expression. Their recognition by computer algorithms is fundamental for understanding gene expression patterns, cell specificity and development. This chapter describes the advanced approaches to identify promoters in animal, plant and bacterial sequences. Also, we discuss an approach to identify statistically significant regulatory motifs in genomic sequences.
|Original language||English (US)|
|Number of pages||27|
|Journal||Methods in molecular biology (Clifton, N.J.)|
|State||Published - Jan 1 2010|
ASJC Scopus subject areas
- Molecular Biology