HESC-derived pancreatic progenitors

Lina Sui*, Guang Hui Liu, Juan Carlos Izpisua Belmonte

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Successful derivation of pancreatic progenitors from human embryonic stem cells (hESCs) in vitro and further differentiation towards functional β cells in vivo may create the possibility of using hESC-derived pancreatic progenitors (PPs), instead of derived β cells, as an alternative transplantable source in β cell replacement therapy. Here we discuss present approaches, as well as future alternatives, in the fields of basic and clinic research on β cell differentiation, derivation and transplantation.

Original languageEnglish (US)
Pages (from-to)592-594
Number of pages3
JournalCell Research
Volume23
Issue number5
DOIs
StatePublished - May 1 2013

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology

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