Gold-catalyzed oxidation of substituted phenols by hydrogen peroxide

Yohan Cheneviere, Valerie Caps, Alain Tuel

Research output: Contribution to journalArticlepeer-review

24 Scopus citations

Abstract

Gold nanoparticles deposited on inorganic supports are efficient catalysts for the oxidation of various substituted phenols (2,6-di-tert-butyl phenol and 2,3,6-trimethyl phenol) with aqueous hydrogen peroxide. By contrast to more conventional catalysts such as Ti-containing mesoporous silicas, which convert phenols to the corresponding benzoquinones, gold nanoparticles are very selective to biaryl compounds (3,3′,5,5′-tetra-tert-butyl diphenoquinone and 2,2′,3,3′,5,5′-hexamethyl-4,4′- biphenol, respectively). Products yields and selectivities depend on the solvent used, the best results being obtained in methanol with yields >98%. Au offers the possibility to completely change the selectivity in the oxidation of substituted phenols and opens interesting perspectives in the clean synthesis of biaryl compounds for pharmaceutical applications. © 2010 Elsevier B.V. All rights reserved.
Original languageEnglish (US)
Pages (from-to)129-134
Number of pages6
JournalApplied Catalysis A: General
Volume387
Issue number1-2
DOIs
StatePublished - Oct 20 2010

ASJC Scopus subject areas

  • Catalysis
  • Process Chemistry and Technology

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