Gold-catalyzed diyne cycloisomerizations involving carbene/alkyne metathesis have been the focal point of attention for the past few years as it offers great potential to build complex polycyclic architectures. However, the design of novel cycloisomerizations has been mostly limited to 1,5/1,6-diynes and has remained very challenging to apply for higher 1,n-diynes. Herein, we disclose an unprecedented cycloisomerization of pyridine-bridged 1,8-diynes involving carbene/alkyne metathesis to access luminescent cycl[3.2.2]azines.
Bibliographical noteKAUST Repository Item: Exported on 2020-10-01
Acknowledgements: Generous financial support by the Council of Scientific and Industrial Research (CSIR), New Delhi [File No. 02(0336)/ 18/EMR-II] is gratefully acknowledged. We thank Dr. Apurba Lal Koner, IISER Bhopal, for helping us in the determination of photophysical properties of fluorophores. C.C.C. and S.B. thank UGC for the award of junior and senior research fellowships, respectively. A.G.T. thanks IISER Bhopal for a junior research fellowship.