Gibberellic acid and cGMP-dependent transcriptional regulation in arabidopsis thaliana

René Bastian, Adam Sean Dawe, Stuart Kurt Meier, Ndiko N. Ludidi, Vladimir B. Bajic, Christoph A Gehring

Research output: Contribution to journalArticlepeer-review

29 Scopus citations

Abstract

An ever increasing amount of transcriptomic data and analysis tools provide novel insight into complex responses of biological systems. Given these resources we have undertaken to review aspects of transcriptional regulation in response to the plant hormone gibberellic acid (GA) and its second messenger guanosine 3',5'-cyclic monophosphate (cGMP) in Arabidopsis thaliana, both wild type and selected mutants. Evidence suggests enrichment of GA-responsive (GARE) elements in promoters of genes that are transcriptionally upregulated in response to cGMP but downregulated in a GA insensitive mutant (ga1-3). In contrast, in the genes upregulated in the mutant, no enrichment in the GARE is observed suggesting that GARE motifs are diagnostic for GA-induced and cGMP-dependent transcriptional upregulation. Further, we review how expression studies of GA-dependent transcription factors and transcriptional networks based on common promoter signatures derived from ab initio analyses can contribute to our understanding of plant responses at the systems level. © 2010 Landes Bioscience.
Original languageEnglish (US)
Pages (from-to)224-232
Number of pages9
JournalPlant signaling & behavior
Volume5
Issue number3
DOIs
StatePublished - Oct 31 2014

ASJC Scopus subject areas

  • Plant Science

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