Genomic evidence for the Pleistocene and recent population history of Native Americans

Maanasa Raghavan, Matthias Steinrücken, Kelley Harris, Stephan Schiffels, Simon Rasmussen, Michael DeGiorgio, Anders Albrechtsen, Cristina Valdiosera, María C. Ávila-Arcos, Anna Sapfo Malaspinas, Anders Eriksson, Ida Moltke, Mait Metspalu, Julian R. Homburger, Jeff Wall, Omar E. Cornejo, J. Víctor Moreno-Mayar, Thorfinn S. Korneliussen, Tracey Pierre, Morten RasmussenPaula F. Campos, Peter De Barros Damgaard, Morten E. Allentoft, John Lindo, Ene Metspalu, Ricardo Rodríguez-Varela, Josefina Mansilla, Celeste Henrickson, Andaine Seguin-Orlando, Helena Malmstöm, Thomas Stafford, Suyash S. Shringarpure, Andrés Moreno-Estrada, Monika Karmin, Kristiina Tambets, Anders Bergström, Yali Xue, Vera Warmuth, Andrew D. Friend, Joy Singarayer, Paul Valdes, Francois Balloux, Ilán Leboreiro, Jose Luis Vera, Hector Rangel-Villalobos, Davide Pettener, Donata Luiselli, Loren G. Davis, Evelyne Heyer, Christoph P E Zollikofer, Marcia S. Ponce De León, Colin I. Smith, Vaughan Grimes, Kelly Anne Pike, Michael Deal, Benjamin T. Fuller, Bernardo Arriaza, Vivien Standen, Maria F. Luz, Francois Ricaut, Niede Guidon, Ludmila Osipova, Mikhail I. Voevoda, Olga L. Posukh, Oleg Balanovsky, Maria Lavryashina, Yuri Bogunov, Elza Khusnutdinova, Marina Gubina, Elena Balanovska, Sardana Fedorova, Sergey Litvinov, Boris Malyarchuk, Miroslava Derenko, M. J. Mosher, David Archer, Jerome Cybulski

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    222 Scopus citations

    Abstract

    How and when the Americas were populated remains contentious. Using ancient and modern genome-wide data, we found that the ancestors of all present-day Native Americans, including Athabascans and Amerindians, entered the Americas as a single migration wave from Siberia no earlier than 23 thousand years ago (ka) and after no more than an 8000-year isolation period in Beringia. After their arrival to the Americas, ancestral Native Americans diversified into two basal genetic branches around 13 ka, one that is now dispersed across North and South America and the other restricted to North America. Subsequent gene flow resulted in some Native Americans sharing ancestry with present-day East Asians (including Siberians) and, more distantly, Australo-Melanesians. Putative "Paleoamerican" relict populations, including the historical Mexican Pericúes and South American Fuego-Patagonians, are not directly related to modern Australo-Melanesians as suggested by the Paleoamerican Model. © 2015, American Association for the Advancement of Science. All rights reserved.
    Original languageEnglish (US)
    Pages (from-to)aab3884-aab3884
    Number of pages1
    JournalScience
    Volume349
    Issue number6250
    DOIs
    StatePublished - Jul 21 2015

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