From iron oxide nanoparticles towards advanced iron-based inorganic materials designed for biomedical applications

Albert Figuerola, Riccardo Di Corato, Liberato Manna, Teresa Pellegrino*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

367 Scopus citations

Abstract

In the last decade the progress achieved on the synthesis of inorganic nanostructures has been accompanied by the parallel exploitation of these systems in various fields, among them are biology and medicine. We provide here an overview of the iron-based inorganic nanostructured materials that have been developed and tested in these fields. We will highlight the major concepts on the preparation, physical properties and applications of such nanostructures, starting from the most investigated iron oxide nanoparticles. We will describe then the new generation of inorganic hybrid nanostructures, which are structures that integrate in each nano-object multiple inorganic nanocrystals of different materials. In our discussion we will focus on those works that have provided a sound proof of concept on the potential of the various systems as diagnostic and therapeutic agents.

Original languageEnglish (US)
Pages (from-to)126-143
Number of pages18
JournalPharmacological Research
Volume62
Issue number2
DOIs
StatePublished - Aug 1 2010

Keywords

  • Inorganic nanostructures
  • Iron oxide nanoparticles
  • Magnetic nanoparticles
  • Multifunctional hybrid materials

ASJC Scopus subject areas

  • Pharmacology
  • Medicine(all)

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