First total synthesis of cryptomisrine

Erwan Arzel, Patrick Rocca*, Francis Marsais, Alain Godard, Guy Quéguiner

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    41 Scopus citations

    Abstract

    The first total synthesis of cryptomisrine, a novel indolo[3,2- b]quinoline dimeric alkaloid from Cryptolepis sanguinolenta, is reported. The approach is based on a convergent methodology which involves a new halogen- dance reaction in quinoline series connected to a cross-coupling reaction.

    Original languageEnglish (US)
    Pages (from-to)12149-12156
    Number of pages8
    JournalTetrahedron
    Volume55
    Issue number41
    DOIs
    StatePublished - Oct 8 1999

    Keywords

    • Coupling reactions
    • Halogen and compounds
    • Metallation
    • Polycyclic compounds

    ASJC Scopus subject areas

    • Biochemistry
    • Drug Discovery
    • Organic Chemistry

    Fingerprint Dive into the research topics of 'First total synthesis of cryptomisrine'. Together they form a unique fingerprint.

    Cite this