Fabrication of thulium metal–organic frameworks based smartphone sensor towards arsenical feed additive drug detection: Applicable in food safety analysis

Sathishkumar Chinnapaiyan, Umamaheswari Rajaji, Shen Ming Chen, Ting Yu Liu, Jose De Oliveira Filho, Yo Shiuan Chang

Research output: Contribution to journalArticlepeer-review

Abstract

A portable sensor is needed for the quick screening of additives in food samples, to ensure food safety. The consumption of roxarsone (ROX) contaminated meat increases arsenic toxicity, risk of cancer and neurodegenerative diseases. In this research work, we report the synthesis of thulium (III)-benzene 1,3,5-tricarboxylic acid-based metal-organic framework (Tm-BTC MOF) and its use as an excellent electrocatalyst for the determination of ROX at point-of-care. A hydrothermal procedure was developed for the synthesis of Tm-BTC MOF using a single polarity solvent. A Tm-BTC MOF modified electrode was fabricated and its electrocatalytic sensing ability towards ROX was explored. Three kinds of special chemical interactions form a special affinity between ROX and Tm-BTC MOF. In association with differential pulse voltammetry, the Tm-BTC MOF/GCE showed a low detection limit of 100 pM. The Tm-BTC MOF modified electrode was integrated into a portable sensing device via coupling it with a miniaturized potentiostat (KAUSTat) operated wirelessly by a smartphone. The developed smartphone-based sensor was successful in measuring ROX not only in lab samples but also in real (spiked) food samples. The method can be suitable for on-site testing of food quality and safety in resource-limited settings.
Original languageEnglish (US)
Pages (from-to)139487
JournalElectrochimica Acta
Volume401
DOIs
StatePublished - Oct 26 2021

ASJC Scopus subject areas

  • Chemical Engineering(all)
  • Electrochemistry

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