In this study, we report the direct synthesis of amides and ureas via the catalytic dehydrogenation of volatile alcohols and amines using the Milstein catalyst in a Pd-Ag/ceramic membrane reactor. A series of amides and ureas, which could not be synthesized in an open system by catalytic dehydrogenation coupling, were obtained in moderate to high yields via catalytic dehydrogenation of volatile alcohols and amines. This process could be monitored by the hydrogen produced. Compared to the traditional method of condensation, this catalytic system avoids the stoichiometric pre-activation or in situ activation of reagents, and is a much cleaner process with high atom economy. This methodology, only possible by employing the Pd-Ag/ceramic membrane reactor, not only provides a new environmentally benign synthetic approach of amides and ureas, but is also a potential method for hydrogen storage.
Bibliographical noteKAUST Repository Item: Exported on 2020-10-01
Acknowledgements: We are grateful for the generous financial support from King Abdullah University of Science and Technology. T. C. thanks the Natural Science Foundation of China (21302170) and the Public Projects of Zhejiang Province (2016C33017). G. Z thanks the support of Natural Science Foundation of China (21506243), Shanghai Municipality Sci & Tech Commission (14DZ1203700) and Youth Innovation Promotion Association of CAS (Y624211401).
ASJC Scopus subject areas
- Filtration and Separation
- Materials Science(all)
- Physical and Theoretical Chemistry