Effects of carbon nanotubes on human monocytes

Milena De Nicola*, Silvia Nuccitelli, Daniele Mirabile Gattia, Enrico Traversa, Andrea Magrini, Antonio Bergamaschi, Lina Ghibelli

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

13 Scopus citations

Abstract

Carbon nanotubes are considered to be one of the novel most attractive materials in nanotechnology. Because of their multiple industrial and biomedical applications, thorough studies on their toxicity and biocompatibility become a priority in order to prevent possible health risks. In this study the effects of multiwalled carbon nanotubes (MWCNT) on healthy monocytes from human peripheral blood were investigated. The results indicate that MWCNT exert a cytotoxic effect on monocytes, inducing cell death and increasing the extent of apoptosis induced by a chemotherapic agent. This cytotoxic effect may have important implications, and much attention in terms of evaluation of exposure risks is recommended.

Original languageEnglish (US)
Title of host publicationNatural Compounds and Their Role in Apoptotic Cell Signaling Pathways
Pages600-605
Number of pages6
Volume1171
DOIs
StatePublished - Aug 2009
Externally publishedYes

Publication series

NameAnnals of the New York Academy of Sciences
Volume1171
ISSN (Print)0077-8923
ISSN (Electronic)1749-6632

Keywords

  • Apoptosis
  • Cytotoxicity
  • Human monocytes
  • MWCNT

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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