Effective synthesis of 2,5-disubstituted tetrahydrofurans from glycerol by catalytic alkylation of ketones

Magnus Rueping*, Vilas B. Phapale

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

30 Scopus citations

Abstract

The [IrCl(cod)] 2 catalyzed α-alkylation of substituted acetophenones with solketal followed by reduction and iron mediated cyclization provides 2,5-disubstituted tetrahydrofurans.

Original languageEnglish (US)
Pages (from-to)55-57
Number of pages3
JournalGreen Chemistry
Volume14
Issue number1
DOIs
StatePublished - Jan 1 2012

ASJC Scopus subject areas

  • Environmental Chemistry
  • Pollution

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