Dysprosium-containing layered double hydroxides nanoparticles intercalated with biologically active species as an approach for theranostic systems

Jenny Arratia-Quijada, Cecilia Sánchez Jiménez, Andrei Gurinov, Armando Pérez Centeno, Israel Ceja Andrade, Gregorio Guadalupe Carbajal Arízaga

    Research output: Contribution to journalArticlepeer-review

    11 Scopus citations

    Abstract

    A layered double hydroxide structure including dysprosium cations was prepared by co-precipitation. The nanoparticles showed a linear relationship with the reciprocal relaxation spin-lattice (T1) time of water protons which is reflected as contrast in aqueous suspensions analyzed by magnetic resonance imaging. The interlayer space of dysprosium containing LDH was successfully intercalated with folate, ibuprofen and gallate ions, which are key molecules for recognition of some cancer cells and treatment of diseases. The paramagnetic property of the dysprosium-containing LDH detected in this work beside the ability to transport drugs open up the opportunity to design theranostic materials in a single crystal phase with nanometric dimensions.
    Original languageEnglish (US)
    Pages (from-to)7-12
    Number of pages6
    JournalMaterials Science and Engineering: B
    Volume203
    DOIs
    StatePublished - Oct 25 2015

    ASJC Scopus subject areas

    • Mechanics of Materials
    • Materials Science(all)
    • Mechanical Engineering
    • Condensed Matter Physics

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