Dynamics of acoustic droplet vaporization in gas embolotherapy

Adnan Qamar*, Zheng Z. Wong, J. Brian Fowlkes, Joseph L. Bull

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

59 Scopus citations

Abstract

Acoustic droplet vaporization is investigated in a theoretical model. This work is motivated by gas embolotherapy, a developmental cancer treatment involving tumor infarction with gas microbubbles that are selectively formed from liquid droplets. The results indicate that there exists a threshold value for initial droplet size below which the bubble evolution is oscillatory and above which it is smooth and asymptotic, and show that the vaporization process affects the subsequent microbubble expansion. Dampening of the bubble expansion is observed for higher viscosity and surface tension, with effects more pronounced for droplet size less than 6 μm in radius.

Original languageEnglish (US)
Article number143702
JournalApplied Physics Letters
Volume96
Issue number14
DOIs
StatePublished - Apr 27 2010

ASJC Scopus subject areas

  • Physics and Astronomy (miscellaneous)

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