DNA Profiling Methods and Tools: A Review

Emad Alamoudi, Rashid Mehmood, Aiiad Albeshri, Takashi Gojobori

Research output: Chapter in Book/Report/Conference proceedingConference contribution

13 Scopus citations

Abstract

DNA typing or profiling is a widely used practice in various forensic laboratories, used, for example, in sexual assault cases when the source of DNA mixture can combine different individuals such as the victim, the criminal, and the victim’s partner. DNA typing is considered one of the hardest problem in the forensic science domain, and it is an active area of research. The computational complexity of DNA typing increases significantly with the number of unknowns in the mixture. Different methods have been developed and implemented to address this problem. However, its computational complexity has been the major deterring factor holding its advancements and applications. In this paper, we review DNA profiling methods and tools with a particular focus on their computational performance and accuracy. Faster interpretations of DNA mixtures with a large number of unknowns and higher accuracies are expected to open up new frontiers for this area.
Original languageEnglish (US)
Title of host publicationLecture Notes of the Institute for Computer Sciences, Social Informatics and Telecommunications Engineering
PublisherSpringer Nature
Pages216-231
Number of pages16
ISBN (Print)9783319941790
DOIs
StatePublished - Jul 22 2018

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