A direct process for the trifluoromethylthiolation of allylic and benzylic alcohols under mild conditions has been developed. A wide range of free alcohols underwent nucleophilic substitution in the presence of stable CuSCF 3 and BF 3 ·Et 2 O to give the corresponding products in good to excellent yields.
- nucleophilic substitution
- trifluoromethyl sulfenylation
ASJC Scopus subject areas
- Organic Chemistry