Design of the monolithic polymers used in capillary electrochromatography columns

Frantisek Svec*, Eric C. Peters, David Sýkora, Jean Frechet

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

250 Scopus citations

Abstract

Monolithic columns for capillary electrochromatography (CEC) are receiving quite remarkable attention. Both the simplicity of the in situ preparation and the large number of readily available chemistries make the monolithic separation media a vital alternative to capillary columns packed with particulate materials. This review summarizes the current state-of-the-art in this rapidly growing area of CEC with a focus on monolithic capillary columns prepared from synthetic polymers. Recent achievements in column technologies for both high-performance liquid chromatography and capillary electrophoresis are used as the starting point to highlight the influence of these well established analytical methods on the development of monolithic capillary columns for CEC. The effects of individual variables on the separation properties of monolithic capillaries are discussed in detail. The analytical potential of these columns is demonstrated with separations involving various families of compounds in different chromatographic modes. Copyright (C) 2000 Elsevier Science B.V.

Original languageEnglish (US)
Pages (from-to)3-29
Number of pages27
JournalJournal of Chromatography A
Volume887
Issue number1-2
DOIs
StatePublished - Jul 28 2000

Keywords

  • Electrochromatography
  • Monolithic columns
  • Polymers, monolithic
  • Reviews

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Design of the monolithic polymers used in capillary electrochromatography columns'. Together they form a unique fingerprint.

Cite this