Crystal-state studies on p-toluenesulfonates of N-oxyimides - A possible structural basis of serine proteases inhibition

Piotr Stefanowicz, Lukasz Jaremko*, Mariusz Jaremko, Tadeusz Lis

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

A series of p-toluenesulfonates of N-oxyimides has been synthesized and their X-ray structures show a flattened pyramidal geometry of the hydroxyimide ring nitrogen. This structural feature is considered to be responsible for a specific chemical reactivity towards nucleophiles and inhibitory properties against proteases of these compounds.

Original languageEnglish (US)
Pages (from-to)258-265
Number of pages8
JournalNew Journal of Chemistry
Volume30
Issue number2
DOIs
StatePublished - Feb 20 2006
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Materials Chemistry

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