CovMT: an interactive SARS-CoV-2 mutation tracker, with a focus on critical variants.

Intikhab Alam, Aleksandar Radovanovic, Roberto Incitti, Allan A Kamau, Mohammed Alarawi, Esam I Azhar, Takashi Gojobori

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

The number of confirmed SARS-CoV-2 cases worldwide has now reached around 100 million, with 2·1 million reported deaths1 and more than 450 000 SARS-CoV-2 genomes already sequenced. It is vital to keep track of mutations in the genome of SARS-CoV-2, especially in the spike protein's receptor binding domain (RBD) region, which could potentially impact disease severity and treatment strategies.2, 3, 4 In the wake of a recent increase in cases with a more infective variant featuring an RBD mutation (N501Y, B.1.1.7) in the UK, countries worldwide are concerned about the spread of this or similar variants. Increasing sequencing efforts and user-friendly mutation tracking systems are needed for timely tracking of SARS-CoV-2 variants.
Original languageEnglish (US)
JournalThe Lancet. Infectious diseases
DOIs
StatePublished - Feb 11 2021

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