Copper-catalyzed trifluoromethylation of arylsulfinate salts using an electrophilic trifluoromethylation reagent

Xiaoxi Lin, Guimei Wang, Huaifeng Li, Yuanyuan Huang, Weiming He, Dandan Ye, Kuo-Wei Huang, Yaofeng Yuan, Zhiqiang Weng

Research output: Contribution to journalArticlepeer-review

29 Scopus citations

Abstract

A copper-catalyzed method for the trifluoromethylation of arylsulfinates with Togni's reagent has been developed, affording aryltrifluoromethylsulfones in moderate to good yields. A wide range of functional groups in arylsulfinates are compatible with the reaction conditions. © 2013 Elsevier Ltd. All rights reserved.
Original languageEnglish (US)
Pages (from-to)2628-2632
Number of pages5
JournalTetrahedron
Volume69
Issue number12
DOIs
StatePublished - Mar 2013

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

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