Combinatorial 'library on bead' approach to polymeric materials with vastly enhanced chiral recognition

Peter Murer, Kevin Lewandowski, Frantisek Svec, Jean M J Fréchet*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

29 Scopus citations

Abstract

A general screening method for enantiomer recognition is introduced for the rapid preparation of novel chiral stationary phases for HPLC in which libraries of mixed chiral selectors are immobilized on polymer beads and the resulting chiral phases tested in the separation of racemic targets followed by deconvolution to afford an optimized separation medium.

Original languageEnglish (US)
Pages (from-to)2559-2560
Number of pages2
JournalChemical Communications
Issue number23
StatePublished - Dec 7 1998
Externally publishedYes

ASJC Scopus subject areas

  • Chemistry(all)

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