Characterization of solid UV cross-linked PEGDA for biological applications

David Castro, Patrick Ingram, Rimantas Kodzius, David Conchouso Gonzalez, Euisik Yoon, Ian G. Foulds

Research output: Chapter in Book/Report/Conference proceedingConference contribution

17 Scopus citations

Abstract

This paper reports on solid UV cross-linked Poly(ethylene)-glycol-diacrylate (PEGDA) as a material for microfluidic devices for biological applications. We have evaluated biocompatibility of PEGDA through two separate means: 1) by examining cell viability and attachment on cross-linked PEGDA surfaces for cell culture applications, and 2) by determining if cross-linked PEGDA inhibits the polymerase chain reaction (PCR) processes for on-chip PCR. Through these studies a correlation has been found between degree of curing and cell viability, attachment, as well as on PCR outcome.
Original languageEnglish (US)
Title of host publication2013 IEEE 26th International Conference on Micro Electro Mechanical Systems (MEMS)
PublisherInstitute of Electrical and Electronics Engineers (IEEE)
Pages457-460
Number of pages4
ISBN (Print)978-146735655-8
DOIs
StatePublished - Mar 20 2013

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