Characteristic distribution of bases and codons around the initiation and termination codons in whole reading frames in bacteria and yeast genomes.

H. Watanabe*, Takashi Gojobori, M. Terabe, M. Wakiyama, K. Miura

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Recently the complete nucleotide sequence of the entire genome was determined for yeast and a few kinds of bacterium. To see characteristic features of base sequence in the cistron (actually the open reading frame, ORF) and in the regions around a cistron (ORF), the biases of appearance frequency of bases from the base ratio were studied statistically. In the regions before the base biases were observed. The characteristic base distribution patterns were similar to all the cases of bacteria, but different from yeast. The base biases are reflected on the appearance frequency of amino acids near the N-termini and C-termini of proteins. The characteristic biases found in the amino acid sequence of the N-terminal part of bacteria proteins are different from that in yeast proteins.

Original languageEnglish (US)
Pages (from-to)297-298
Number of pages2
JournalNucleic acids symposium series
Issue number37
StatePublished - Jan 1 1997

ASJC Scopus subject areas

  • Medicine(all)

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