Cellular Internalization and Biocompatibility of Periodic Mesoporous Organosilica Nanoparticles with Tunable Morphologies: From Nanospheres to Nanowires

Yevhen Fatieiev, Jonas G. Croissant, Kholod Alamoudi, Niveen M. Khashab

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

This work describes the sol-gel syntheses of para-substituted phenylene-bridged periodic mesoporous organosilica (PMO) nanoparticles (NPs) with tunable morphologies ranging from nanowires to nanospheres. The findings show the key role of the addition of organic co-solvents in the aqueous templates on the final morphologies of PMO NPs. Other factors such as the temperature, the stirring speed, and the amount of organic solvents also influence the shape of PMO NPs. The tuning of the shape of the PMO nanomaterials made it possible to study the influence of the particle morphology on the cellular internalization and biocompatibility.
Original languageEnglish (US)
Pages (from-to)631-637
Number of pages7
JournalChemPlusChem
Volume82
Issue number4
DOIs
StatePublished - Jan 31 2017

Fingerprint Dive into the research topics of 'Cellular Internalization and Biocompatibility of Periodic Mesoporous Organosilica Nanoparticles with Tunable Morphologies: From Nanospheres to Nanowires'. Together they form a unique fingerprint.

Cite this