Cancer du sein: Prédictivité de la réponse à la chimiothérapie néoadjuvante

Translated title of the contribution: Breast cancer: Nomograms to predict pathologic response after preoperative chemotherapy

Roman Rouzier*, Charles Coutant, Roberto Incitti, René Natowicz, Georges Chahine, Serge Uzan, David Atallah

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

If the benefit of adjuvant chemotherapy may be determined at the level of a population, to determine the real chemosensitivity of a tumor at the individual level is impossible. The concept of neoadjuvant chemotherapy in patients with localized breast cancer is interesting because it helps to know the chemosensitivity of a tumor "in vivo". It is possible to use a single criterion to predict the effectiveness of targeted therapies. The chemotherapy is not a targeted therapy, and to determine a biological predictive marker of the response has been impossible so far. The development of mathematical models and use of molecular biology may help to predict chemosensitivity. Initial results are promising. The validation of published works is necessary, but applications are numerous.

Translated title of the contributionBreast cancer: Nomograms to predict pathologic response after preoperative chemotherapy
Original languageFrench
Pages (from-to)89-92
Number of pages4
JournalJournal Medical Libanais
Volume57
Issue number2
StatePublished - Apr 2009
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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