Brønsted Base Assisted Photoredox Catalysis: Proton Coupled Electron Transfer for Remote C−C Bond Formation via Amidyl Radicals

Jiaqi Jia, Yee Ann Ho, Raoul F. Bülow, Magnus Rueping

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

The synthesis of alkyne- and alkene-decorated lactams has been achieved through a photoredox-initiated radical cascade reaction. The developed Brønsted base assisted, photoredox-catalyzed, intramolecular 5-exo-trig cyclization/intermolecular radical addition/elimination reaction provides facile access to functionalized γ-lactams, with good functional group tolerance and high yields.
Original languageEnglish (US)
Pages (from-to)14054-14058
Number of pages5
JournalChemistry - A European Journal
Volume24
Issue number53
DOIs
StatePublished - Aug 27 2018

Fingerprint

Dive into the research topics of 'Brønsted Base Assisted Photoredox Catalysis: Proton Coupled Electron Transfer for Remote C−C Bond Formation via Amidyl Radicals'. Together they form a unique fingerprint.

Cite this