Bioconjugated silicon quantum dots from one-step green synthesis

Romuald Intartaglia*, Annette Barchanski, Komal Bagga, Alessandro Genovese, Gobind Das, Philipp Wagener, Enzo Di Fabrizio, Alberto Diaspro, Fernando Brandi, Stephan Barcikowski

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

66 Scopus citations

Abstract

Biofunctionalized silicon quantum dots were prepared through a one step strategy avoiding the use of chemical precursors. UV-Vis spectroscopy, Raman spectroscopy and HAADF-STEM prove oligonucleotide conjugation to the surface of silicon nanoparticle with an average size of 4 nm. The nanoparticle size results from the size-quenching effect during in situ conjugation. Photoemissive properties, conjugation efficiency and stability of these pure colloids were studied and demonstrate the bio-application potential, e.g. for nucleic acid vector delivery with semiconducting, biocompatible nanoparticles.

Original languageEnglish (US)
Pages (from-to)1271-1274
Number of pages4
JournalNanoscale
Volume4
Issue number4
DOIs
StatePublished - Feb 21 2012
Externally publishedYes

ASJC Scopus subject areas

  • Materials Science(all)

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