Astrocytes couple synaptic activity to glucose utilization in the brain

Pierre J. Magistretti*, Luc Pellerin

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

191 Scopus citations

Abstract

Astrocytes have functional characteristics that make them particularly well suited to couple glutamate uptake from the synaptic cleft to Na+-K+-ATPase activation and glucose utilization. The changes in glucose metabolism associated with these processes may provide signals detected by positron emission tomography.

Original languageEnglish (US)
Pages (from-to)177-182
Number of pages6
JournalNews in Physiological Sciences
Volume14
Issue number5
StatePublished - Oct 1999
Externally publishedYes

ASJC Scopus subject areas

  • Physiology

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