Analysis of aromatic polyether dendrimers and dendrimer-linear block copolymers by matrix-assisted laser desorption ionization mass spectrometry

Jeffrey W. Leon*, Jean M.J. Fréchet

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

52 Scopus citations

Abstract

Polyether dendrimers with differing chain end functionalites and molecular topologies were analyzed by MALDI-TOF mass spectrometry. The success of this analytical method is highly dependent on the type of matrix and sample preparation used. Ester and perdeuterophenyl terminated dendrimers with molecular weights up to 14,000 amu were successfully analyzed using an indoleacrylic acid matrix in tetrahydrofuran. Hybrid block copolymers consisting of linear polystyrene or poly (ethylene glycol) chains attached to one or two dendrimers gave spectra with oligomeric resolution in matrices of t-retinoic acid and 2-nitrophenyl octyl ether respectively. The MALDI-TOF results provide access to molecular weight distribution data confirming the results of size exclusion chromatography (SEC) analysis.

Original languageEnglish (US)
Pages (from-to)449-455
Number of pages7
JournalPolymer Bulletin
Volume35
Issue number4
DOIs
StatePublished - Oct 1995
Externally publishedYes

ASJC Scopus subject areas

  • Chemistry(all)
  • Condensed Matter Physics
  • Polymers and Plastics
  • Materials Chemistry

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