An answer in the palm of your hand: Microfluidics for analytical applications

Yolanda Fintschenko*, Wen Yee Choi, Eric B. Cummings, Jean Frechet, Julia A. Fruetel, Emily F. Hilder, Dieudonne A. Mair, Timothy J. Shepodd, Frantisek Svec

*Corresponding author for this work

Research output: Contribution to journalConference articlepeer-review

4 Scopus citations

Abstract

We have applied CZE and CEC in microfluidic devices to a number of analytical problems including the analysis of chemical warfare agents, polycyclic aromatic hydrocarbons, and proteins. In addition to developments in the areas of separations, we are also heavily involved in the "front-end" of analytical systems particularly in the area of sample preconcentration. We have a particular interest in the concentration of a wide range of molecules including small molecules, biopolymers, and cells. Our current toolbox includes a microfluidic platform known as Liquid Phase μChemLab™ developed by a team at Sandia for protein analysis. This platform has been demonstrated with protein biotoxins, CW agent degradation products, protein preconcentration, and is suitable for other targets. Additionally, electrodeless dielectrophoresis technology developed at Sandia is an attractive alternative to filters for cell concentration.

Original languageEnglish (US)
Pages (from-to)196-207
Number of pages12
JournalProceedings of SPIE - The International Society for Optical Engineering
Volume4982
DOIs
StatePublished - May 26 2003
EventMicrofluidics, BioMEMS, and Medical Microsystems - San Jose, CA, United States
Duration: Jan 27 2003Jan 29 2003

Keywords

  • CEC
  • CZE
  • Dielectrophoresis
  • Microfluidics
  • Platform
  • Porous polymer monolith
  • Preconcentrator
  • μChemLab™

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

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