An air-stable copper reagent for nucleophilic trifluoromethylthiolation of aryl halides

Zhiqiang Weng, Weiming He, Chaohuang Chen, Richmond Lee, Davin Tan, Zhiping Lai, Dedao Kong, Yaofeng Yuan, Kuo-Wei Huang

Research output: Contribution to journalArticlepeer-review

242 Scopus citations

Abstract

A series of copper(I) trifluoromethyl thiolate complexes have been synthesized from the reaction of CuF2 with Me3SiCF 3 and S8 (see scheme; Cu red, F green, N blue, S yellow). These air-stable complexes serve as reagents for the efficient conversion of a wide range of aryl halides into the corresponding aryl trifluoromethyl thioethers in excellent yields. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Original languageEnglish (US)
Pages (from-to)1548-1552
Number of pages5
JournalAngewandte Chemie International Edition
Volume52
Issue number5
DOIs
StatePublished - Dec 12 2012

ASJC Scopus subject areas

  • Chemistry(all)
  • Catalysis

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