A simple method for controlling dendritic architecture and diversity: A parallel monomer combination approach

A. W. Freeman, L. A.J. Chrisstoffels, Jean Frechet*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

45 Scopus citations

Abstract

A novel parallel monomer combination approach to manipulating the architectural disposition of dendritic macromolecules is described. It harnesses the synthetic speed and power of the double-stage convergent growth approach and classical parallel synthesis to prepare diverse series of dendrimers that possess a predetermined number and arrangement of 'internal' functional moieties. This methodology is applied for the preparation of a novel family of poly(benzyl ether) dendrimers possessing 1-15 'internal' allyloxy groups, which are displayed in a highly controlled, layer-specific, generational manner.

Original languageEnglish (US)
Pages (from-to)7612-7617
Number of pages6
JournalJournal of Organic Chemistry
Volume65
Issue number22
DOIs
StatePublished - Nov 3 2000

ASJC Scopus subject areas

  • Organic Chemistry

Cite this