A simple in situ microfluidic procedure to create multivalent biofunctionalized surfaces

G. Perozziello*, G. Simone, M. Francardi, Rosanna La Rocca, N. Malara, P. Candeloro, E. Carbone, E. Di Fabrizio, A. Manz

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations

Abstract

In this study we propose a fast, simple method to biofunctionalize microfluidic systems for cellomic investigations based on microfluidic protocols. The combination of biofunctiolased surfaces and microfluidics gived the opportunity to create devices that can better diagnose disease, or discover cell functionalities. The developed systems can be used for different application in the cellomic fields In this work, they were tested to sort tumor cells and change tumor cell phenotypes. The results showed a high flexibility of the biofunctionalized protocols to create such systems in short time, with low reagent consumption and in a standard manner.

Original languageEnglish (US)
Title of host publication15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
Pages1837-1839
Number of pages3
Volume3
StatePublished - 2011
Externally publishedYes
Event15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011 - Seattle, WA, United States
Duration: Oct 2 2011Oct 6 2011

Other

Other15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
CountryUnited States
CitySeattle, WA
Period10/2/1110/6/11

Keywords

  • Biofunctionalization
  • Cell handling

ASJC Scopus subject areas

  • Control and Systems Engineering

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