A route to hydroxylfluorenes: TsOH-mediated condensation reactions of 1,3-diketones with propargylic alcohols

Liangfeng Yao, Davin Tan, Xiaohe Miao, Kuo-Wei Huang

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

An efficient method of preparing hydroxylfluorenes by TsOH-mediated tandem alkylation/rearrangements of propargylic alcohols with 1,3-diketones is described. These reactions are accomplished in moderate to good yields under mild conditions to offer a straightforward and convenient one step synthetic route to hydroxylfluorene derivatives through a plausible mechanism involving a sequence of dehydration, addition, rearrangement and aromatization. This journal is © The Royal Society of Chemistry 2012.
Original languageEnglish (US)
Pages (from-to)7594
JournalRSC Advances
Volume2
Issue number19
DOIs
StatePublished - 2012

ASJC Scopus subject areas

  • Chemical Engineering(all)
  • Chemistry(all)

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