A proposal for a gene functions wiki

Robert Hoehndorf*, Kay Prüfer, Michael Backhaus, Heinrich Herre, Janet Kelso, Frank Loebe, Johann Visagie

*Corresponding author for this work

Research output: Contribution to journalConference articlepeer-review

10 Scopus citations

Abstract

Large knowledge bases integrating different domains can provide a foundation for new applications in biology such as data mining or automated reasoning. The traditional approach to the construction of such knowledge bases is manual and therefore extremely time consuming. The ubiquity of the internet now makes large-scale community collaboration for the construction of knowledge bases, such as the successful online encyclopedia "Wikipedia", possible. We propose an extension of this model to the collaborative annotation of molecular data. We argue that a semantic wiki provides the functionality required for this project since this can capitalize on the existing representations in biological ontologies. We discuss the use of a different relationship model than the one provided by RDF and OWL to represent the semantic data. We argue that this leads to a more intuitive and correct way to enter semantic content in the wiki. Furthermore, we show how formal ontologies could be used to increase the usability of the software through type-checking and automatic reasoning.

Original languageEnglish (US)
Pages (from-to)669-678
Number of pages10
JournalLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume4277 LNCS - I
StatePublished - Jan 1 2006
EventOTM 2006 Workshops - OTM Confederated International Workshops - Montpellier, France
Duration: Oct 29 2006Nov 3 2006

ASJC Scopus subject areas

  • Theoretical Computer Science
  • Computer Science(all)

Fingerprint

Dive into the research topics of 'A proposal for a gene functions wiki'. Together they form a unique fingerprint.

Cite this