A magnetic particle micro-trap for large trapping surfaces

Chinthaka Pasan Gooneratne, Cai Liang, Ioanna Giouroudi, Jürgen Kosel

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Scopus citations

Abstract

Manipulation of micron-size magnetic particles of the superparamagnetic type contributes significantly in many applications like controlling the antibody/antigen binding process in immunoassays. Specifically, more target biomolecules can be attached/tagged and analyzed since the three dimensional structure of the magnetic particles increases the surface to volume ratio. Additionally, such biomolecular-tagged magnetic particles can be easily manipulated by an external magnetic field due to their superparamagnetic behavior. Therefore, magnetic particle- based immunoassays are extensively applied in micro-flow cytometry. The design of a square-loop micro-trap as a magnetic particle manipulator as well as numerical and experimental analysis is presented. Experimental results showed that the micro-trap could successfully trap and concentrate magnetic particles from a large to a small area with a high spatial range.
Original languageEnglish (US)
Title of host publicationProcedia Engineering
PublisherElsevier BV
Pages1201-1204
Number of pages4
DOIs
StatePublished - Jan 9 2012

Fingerprint Dive into the research topics of 'A magnetic particle micro-trap for large trapping surfaces'. Together they form a unique fingerprint.

Cite this