A General Approach to the Basiliolide/Transtaganolide Natural Products: Total Syntheses of Basiliolide B, epi-8-Basiliolide B, Transtaganolide C, and Transtaganolide D

Hosea M. Nelson, Kei Murakami, Scott C. Virgil, Brian M. Stoltz

Research output: Contribution to journalArticlepeer-review

26 Scopus citations

Abstract

(Figure Presented) In a flash: The total synthesis of transtaganolide and basiliolide natural products is achieved in three steps from achiral, monocyclic esters (see scheme). Featured in the syntheses are an Ireland-Claisen/Diels- Alder cascade and a novel methoxyacetylide coupling/cyclization sequence. © 2011 Wiley-VCH Verlag GmbH & Co. KGaA.
Original languageEnglish (US)
Pages (from-to)3688-3691
Number of pages4
JournalAngewandte Chemie International Edition
Volume50
Issue number16
DOIs
StatePublished - Mar 25 2011
Externally publishedYes

Fingerprint

Dive into the research topics of 'A General Approach to the Basiliolide/Transtaganolide Natural Products: Total Syntheses of Basiliolide B, epi-8-Basiliolide B, Transtaganolide C, and Transtaganolide D'. Together they form a unique fingerprint.

Cite this