A calcium sensor and its interacting protein kinase are global regulators of abscisic acid signaling in Arabidopsis

Yan Guo, Liming Xiong, Chun Peng Song, Deming Gong, Ursula Halfter, Jian Kang Zhu*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

223 Scopus citations

Abstract

The phytohormone abscisic acid (ABA) triggers an oscillation in the cytosolic Ca2+ concentration, which is then perceived by unknown Ca2+ binding proteins to initiate a series of signaling cascades that control many physiological processes, including adaptation to environmental stress. We report here that a Ca2+ binding protein, SCaBP5, and its interacting protein kinase, PKS3, function as global regulators of ABA responses. Arabidopsis mutants with silenced SCaBP5 or PKS3 are hypersensitive to ABA in seed germination, seedling growth, stomatal closing, and gene expression. PKS3 physically interacts with the 2C-type protein phosphatase ABI2 (ABA-insensitive 2) and to a lesser extent with the homologous ABI1 (ABA-insensitive 1) protein. Thus, SCaBP5 and PKS3 are part of a calcium-responsive negative regulatory loop controlling ABA sensitivity.

Original languageEnglish (US)
Pages (from-to)233-244
Number of pages12
JournalDevelopmental Cell
Volume3
Issue number2
DOIs
StatePublished - Jan 1 2002

ASJC Scopus subject areas

  • Molecular Biology
  • Biochemistry, Genetics and Molecular Biology(all)
  • Developmental Biology
  • Cell Biology

Fingerprint

Dive into the research topics of 'A calcium sensor and its interacting protein kinase are global regulators of abscisic acid signaling in Arabidopsis'. Together they form a unique fingerprint.

Cite this