A biocompatible method of decorporation: Bisphosphonate-modified magnetite nanoparticles to remove uranyl ions from blood

Ling Wang, Zhimou Yang, Jinhao Gao, Kerning Xu, Hongwei Gu, Bei Zhang, Xixiang Zhang, Bing Xu*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

190 Scopus citations

Abstract

We report on the use of bisphosphonate to functionalize Fe3O4 magnetic nanoparticles via dopamine (DA) linkage. Using tetraethyl-3-aminopropane-1,1-bisphosphonate (BP) as the functional molecule, we created a system with an Fe3O4-DA-BP nanostructure, which possesses high specificity for removing uranyl ions from water or blood. This work demonstrates that magnetic nanoparticles, combined with specific receptor-ligand interactions, promise a sensitive and rapid platform for the detection, recovery, and decorporation of metal toxins from biological environment.

Original languageEnglish (US)
Pages (from-to)13358-13359
Number of pages2
JournalJournal of the American Chemical Society
Volume128
Issue number41
DOIs
StatePublished - Oct 18 2006

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

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