3D printing of microlenses for aberration correction in GRIN microendoscopes

Andrea Antonini, Serena Bovetti, Claudio Moretti, Francesca Succol, Vijayakumar Palanisamy Rajamanickam, Andrea Bertoncini, Tommaso Fellin, Carlo Liberale

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Two-photon fluorescence microscopy provides high resolution information on the anatomy and function of cellular structures located several hundreds of microns deep within biological tissues. However, light scattering poses a fundamental limit to imaging of deeper areas (> 1.5 mm). Implantable microendoscopic probes based on graded index (GRIN) lenses are widely used tools to perform two-photon fluorescence microscopy in otherwise inaccessible regions[1], but the optical performances of with these probes are limited by intrinsic aberrations.
Original languageEnglish (US)
Title of host publication2017 Conference on Lasers and Electro-Optics Europe & European Quantum Electronics Conference (CLEO/Europe-EQEC)
PublisherOSA - The Optical Society
ISBN (Print)9781509067367
DOIs
StatePublished - Nov 2 2017

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