Computational Bioscience Research Center

Computer, Electrical and Mathematical Science and Engineering

Websitehttps://cb.kaust.edu.sa/Pages/Home.aspx, https://www.facebook.com/cbrckaust, https://twitter.com/CBRC_KAUST

Address

Saudi Arabia

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Profile Information

Scope

The research portfolio of KAUST's Computational Bioscience Research Center (CBRC) encompasses computational biology and bioinformatics with applications in life sciences.

Core activity: Big Data analytics in life sciences

CBRC aims at solving the methodological and practical challenges linked to extracting useful information from Big Data in Biomedicine and Biotechnology. The center focuses on machine learning and high performance computing for efficient knowledge-, data- and text-mining. Computational approaches are integrated with experimental approaches for data generation and validation. Applications are in human health and Biotechnology.

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Stefan Arold
- Biological, Environmental Science and Engineering - Professor, Bioscience
- Bioscience
- Computational Bioscience Research Center
Person: Professor
19972021
Xin Gao
- Computer, Electrical and Mathematical Science and Engineering - Professor, Computer Science; Acting Associate Director, Computational Bioscience Research Center
- Computational Bioscience Research Center
- Computer Science
Person: Associate Professor
20022021
Takashi Gojobori
- Computer, Electrical and Mathematical Science and Engineering - Distinguished Professor, Bioscience; Acting Director, Computational Bioscience Research Center
- Bioscience
- Computational Bioscience Research Center
Person: Distinguished Professor
19792021
Charlotte Hauser
- Biological, Environmental Science and Engineering - Professor, Bioengineering
- Bioengineering
- Computational Bioscience Research Center
Person: Professor
19862021
Robert Hoehndorf
- Computer, Electrical and Mathematical Science and Engineering - Associate Professor, Computer Science
- Computational Bioscience Research Center
- Computer Science
Person: Associate Professor
20062021

28086 Citations
70 h-Index
939 Article
136 Conference contribution
27 Patent
20 Chapter
More

1'-Ribose cyano substitution allows Remdesivir to effectively inhibit nucleotide addition and proofreading during SARS-CoV-2 viral RNA replication.
Zhang, L., Zhang, D., Wang, X., Yuan, C., Li, Y., Jia, X., Gao, X., Yen, H-L., Cheung, P. P-H. & Huang, X., Mar 10 2021, In: Physical chemistry chemical physics : PCCP.
Research output: Contribution to journal › Article › peer-review
Analysis of the effects of related fingerprints on molecular similarity using an eigenvalue entropy approach
Kuwahara, H. & Gao, X., Mar 23 2021, In: Journal of Cheminformatics. 13, 1
Research output: Contribution to journal › Article › peer-review
A Novel Biallelic STING1 Gene Variant Causing SAVI in Two Siblings
Alghamdi, M. A., Mulla, J., Saheb Sharif-Askari, N., Guzmán-Vega, F. J., Arold, S. T., Abd-Alwahed, M., Alharbi, N., Kashour, T. & Halwani, R., Jan 8 2021, In: Frontiers in Immunology. 11
Research output: Contribution to journal › Article › peer-review
Application and evaluation of knowledge graph embeddings in biomedical data
Alshahrani, M., Thafar, M. A. & Essack, M., Feb 18 2021, In: PeerJ Computer Science. 7, p. e341
Research output: Contribution to journal › Article › peer-review
Bi-allelic variants in HOPS complex subunit VPS41 cause cerebellar ataxia and abnormal membrane trafficking.
Sanderson, L. E., Lanko, K., Alsagob, M., AlMass, R., Al-Ahmadi, N., Najafi, M., Al-Muhaizea, M. A., Alzaidan, H., AlDhalaan, H., Perenthaler, E., van der Linde, H. C., Nikoncuk, A., Kühn, N. A., Antony, D., Owaidah, T. M., Raskin, S., Vieira, L. G. D. R., Mombach, R., Ahangari, N., Silveira, T. R. D. & 36 others, Ameziane, N., Rolfs, A., Alharbi, A., Sabbagh, R. M., AlAhmadi, K., Alawam, B., Ghebeh, H., AlHargan, A., Albader, A. A., Binhumaid, F. S., Goljan, E., Monies, D., Mustafa, O. M., Aldosary, M., AlBakheet, A., Alyounes, B., Almutairi, F., Al-Odaib, A., Aksoy, D. B., Basak, A. N., Palvadeau, R., Trabzuni, D., Rosenfeld, J. A., Karimiani, E. G., Meyer, B. F., Karakas, B., Al-Mohanna, F., Arold, S. T., Colak, D., Maroofian, R., Houlden, H., Bertoli-Avella, A. M., Schmidts, M., Barakat, T. S., van Ham, T. J. & Kaya, N., Mar 25 2021, In: Brain : a journal of neurology.
Research output: Contribution to journal › Article › peer-review

Tracking COVID-19 Virus Mutations across the World
Intikhab Alam & Takashi Gojobori
02/25/21
1 item of Media coverage
Press/Media: Press / Media
CovMT could help researchers to track evolution of SARS-CoV-2 mutations
Intikhab Alam & Takashi Gojobori
02/23/21
1 item of Media coverage
Press/Media: Press / Media
CovMT: Tracking virus mutations across the world
Intikhab Alam & Takashi Gojobori
02/21/21 → 02/22/21
3 items of Media coverage
Press/Media: Press / Media
Simulating evolution to understand a hidden switch
Xin Gao & Hiroyuki Kuwahara
01/15/21 → 01/19/21
8 items of Media coverage
Press/Media: Press / Media
Simulating Evolution to Understand a Hidden Genetic Switch
Xin Gao & Hiroyuki Kuwahara
01/18/21
2 items of Media coverage
Press/Media: Press / Media